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Article

Seven transmembrane receptors: something old, something new.

Acta physiologica (Oxford, England) - 1 May 2007

Lefkowitz R J

Abstract excerpt

Receptors for hormones, neurotransmitters, drugs, sensory stimuli and many other agents represent the gateway to cellular metabolism and activity. They regulate virtually all physiological processes in mammals. Yet as recently as 40 years ago their very existence was still in question. One class of receptors, those coupled to G proteins (also known as GPCRs or seven transmembrane receptors) comprise by far the...

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PMID: 17428228
DOI: 10.1111/j.1365-201X.2007.01693.x

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