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Article

Using passenger mutations to estimate the timing of driver mutations and identify mutator alterations.

BMC bioinformatics - 13 Dec 2013

Youn Ahrim, Simon Richard

Abstract excerpt

BACKGROUND: Recent developments in high-throughput genomic technologies make it possible to have a comprehensive view of genomic alterations in tumors on a whole genome scale. Only a small number of somatic alterations detected in tumor genomes are driver alterations which drive tumorigenesis. Mo...

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Source

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Identifiers

PMID: 24330428
DOI: 10.1186/1471-2105-14-363
PMCID: PMC3903072

Genes

BRCA1
PRKDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24330428-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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