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Article

Corrections for mRNA extraction and sample normalization errors find increased mRNA levels may compensate for cancer haplo-insufficiency.

Genes, chromosomes & cancer - 1 Feb 2014

Weaver David A, Nestor-Kalinoski Andrea L, Craig Kristen, Gorris Matthew, Parikh Tejal, Mabry Helen, Allison David C

Abstract excerpt

The relative mRNA levels of differentially expressed (DE) and housekeeping (HK) genes of six aneuploid cancer lines with large-scale genomic changes identified by SNP/SKY analysis were compared with similar genes in diploid cells. The aneuploid cancer lines had heterogeneous genomic landscapes with subdiploid, diploid, and supradiploid regions and higher overall gene copy numbers compared with diploid cells. The...

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Identifiers

PMID: 24327546
DOI: 10.1002/gcc.22133
PMCID: PMC4237174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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