Article
Opioid signaling in mast cells regulates injury responses associated with heterotopic ossification.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Mar 2014
Kan Lixin, Mutso Amelia A, McGuire Tammy L, Apkarian Apkar Vania, Kessler John A
Abstract excerpt
INTRODUCTION: Previous studies found that neuron specific enolase promoter (Nse-BMP4) transgenic mice have increased expression of the nociceptive mediator, substance P and exaggerated local injury responses associated with heterotopic ossification (HO). It is of interest great to know the pain responses in these mice and how the opioid signaling is involved in the downstream events such as mast cell (MC)...
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