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Article

Changes in epidermal growth factor receptor expression during chemotherapy in non-small cell lung cancer.

Cancer chemotherapy and pharmacology - 1 Jan 2014

Jakobsen Jan Nyrop, Santoni-Rugiu Eric, Sørensen Jens Benn

Abstract excerpt

BACKGROUND: Antibodies targeting epidermal growth factor receptor (EGFR), such as cetuximab, may potentially improve outcome in non-small cell lung cancer (NSCLC) patients with high EGFR expression. The EGFR expression may be heterogeneously distributed within tumors, and small biopsies may thus not accurately reveal the EGFR expression. In addition, EGFR expression may also change during chemotherapy. The...

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Identifiers

PMID: 24326616
DOI: 10.1007/s00280-013-2329-0

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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