Article
Identification of EGFR Mutations by Immunohistochemistry with EGFR Mutation-Specific Antibodies in Biopsy and Resection Specimens from Pulmonary Adenocarcinoma.
Cancer research and treatment - 1 Oct 2015
Kim Chi Hong, Kim Seung Hoon, Park Sonya Youngju, Yoo Jinyoung, Kim Sung Kyoung, Kim Hoon Kyo
Abstract excerpt
PURPOSE: Mutation-specific antibodies have recently been developed for identification of epidermal growth factor receptor (EGFR) mutations by immunohistochemistry (IHC). This study was designed to investigate whether the type of specimen (biopsy vs. resection) would make a difference in determining mutation status by IHC, and to evaluate whether biopsies are suitable for detection of mutant EGFR protein....
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