Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations of EGFR or KRAS and expression of chemotherapy-related genes based on small biopsy samples in stage IIIB and IV inoperable non-small cell lung cancer.

Journal of cancer research and clinical oncology - 1 Dec 2014

Deng Li-Li, Deng Hong-Bin, Lu Chang-Lian, Guo Yang, Wang Di, Yan Chun-Hua, Lv Xing, Shao Yu-Xia

Abstract excerpt

PURPOSES: Epidermal growth factor receptor (EGFR) and KRAS mutations may predict the outcome of targeted drug therapy and also may be associated with the efficacy of chemotherapy in patients with non-small cell lung cancer (NSCLC). This report investigated the relation of EGFR or KRAS mutation and expression of chemotherapy-related genes, including excision repair cross-complementing 1 (ERCC1), thymidylate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy
Share to Endonucleases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proto-Oncogene Proteins p21(ras)

Share to ras Proteins

Share to Ribonucleoside Diphosphate Reductase

Share to Thymidylate Synthase

Share to Tubulin

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 24994038
DOI: 10.1007/s00432-014-1751-y

Genes

EGFR
KRAS
ERCC1
TUBB3
TYMS
LCT
RRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations of EGFR or KRAS and expression of chemotherapy-related genes based on small biopsy samples in stage IIIB and IV inoperable non-small cell lung cancer.PMID 24994038Read ↗

Association of EGFR mutation or ALK rearrangement with expression of DNA repair and synthesis genes in never-smoker women with pulmonary adenocarcinoma.Semantic proximity Read ↗

Associations between clinical characteristics and oncogene expression in patients with non-small cell lung cancer.Semantic proximity Read ↗

Molecular Predictors of Response to Chemotherapy in Non-Small Cell Lung CancerSemantic proximity Read ↗

Treatment of non-small-cell lung cancer and pharmacogenomics: where we are and where we are going.Semantic proximity Read ↗

Combined analysis of rearrangement of ALK, ROS1, somatic mutation of EGFR, KRAS, BRAF, PIK3CA, and mRNA expression of ERCC1, TYMS, RRM1, TUBB3, EGFR in patients with non-small cell lung cancer and their clinical significance.Semantic proximity Read ↗

Expression of excision repair cross-complementation group 1 and class III beta-tubulin predict survival after chemotherapy for completely resected non-small cell lung cancer.Semantic proximity Read ↗

Individualized treatment of NSCLC: from research to clinical practice.Semantic proximity Read ↗

mRNA Expression and Clinical Significance of ERCC1, BRCA1, RRM1, TYMS and TUBB3 in Postoperative Patients with Non-Small Cell Lung CancerSemantic proximity Read ↗

The Utility of Thyroid Transcription Factor 1 (TTF-1), Napsin A, Excision Repair Cross-Complementing 1 (ERCC1), Anaplastic Lymphoma Kinase (ALK) and the Epidermal Growth Factor Receptor (EGFR) Expression in Small Biopsy in Prognosis of Patients with Lung Adenocarcinoma - A Retrograde Single-Center Study from Croatia.Semantic proximity Read ↗

Association of epidermal growth factor receptor activating mutations with low ERCC1 gene expression in non-small cell lung cancer.Semantic proximity Read ↗

Disease-free survival of patients after surgical resection of non-small cell lung carcinoma and correlation with excision repair cross-complementation group 1 expression and genotype.Semantic proximity Read ↗

Expression of gemcitabine- and cisplatin-related genes in non-small-cell lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.