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Article

Association of epidermal growth factor receptor activating mutations with low ERCC1 gene expression in non-small cell lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Dec 2010

Gandara David R, Grimminger Peter, Mack Philip C, Lara Primo N, Li Tianhong, Danenberg Peter V, Danenberg Kathleen D

Abstract excerpt

INTRODUCTION: Patients with non-small cell lung cancer (NSCLC) with cancers harboring activating mutations in the epidermal growth factor receptor (EGFR) show improved efficacy from EGFR tyrosine kinase inhibitors. Some clinical studies also suggest enhanced efficacy of platinum-based chemotherap...

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Source

Identifiers

PMID: 20975603
DOI: 10.1097/JTO.0b013e3181fd418d

Genes

EGFR
ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20975603-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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