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Article

Intratumor heterogeneity and chemotherapy-induced changes in EGFR status in non-small cell lung cancer.

Cancer chemotherapy and pharmacology - 1 Feb 2012

Jakobsen Jan Nyrop, Sørensen Jens Benn

Abstract excerpt

INTRODUCTION: Biomarker expression is increasingly being used to customize treatment in non-small cell lung cancer (NSCLC). The choice of systemic treatment usually depends on biomarker expression in the initial diagnostic biopsy taken before initiation of first-line treatment. Chemotherapy induces DNA damages in the tumor cells, and thus, biomarker expression in the tumor after systemic treatment might not be...

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Source

Identifiers

PMID: 22130585
DOI: 10.1007/s00280-011-1791-9

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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