Article
Influence of chemotherapy on EGFR mutation status among patients with non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Sept 2012
Bai Hua, Wang Zhijie, Chen Keneng, Zhao Jun, Lee J Jack, Wang Shuhang, Zhou Qinghua, Zhuo Minglei, Mao Li, An Tongtong, Duan Jianchun, Yang Lu, Wu Meina, Liang Zhen, Wang Yuyan, Kang Xiaozheng, Wang Jie
Abstract excerpt
PURPOSE: EGFR mutation is a predictor of epidermal growth factor receptor-tyrosine kinase inhibitor treatment response in patients with non-small-cell lung cancer (NSCLC). However, it remains unclear whether chemotherapy affects EGFR mutation status in NSCLC. We investigated the influence of chemotherapy on EGFR mutations in plasma and tumor tissues from patients with NSCLC. PATIENTS AND METHODS: Samples were...
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