Association study between SNP rs150689919 in the DNA demethylation gene, TET1, and Parkinson's disease in Chinese Han population.

doi:10.1186/1471-2377-13-196

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Association study between SNP rs150689919 in the DNA demethylation gene, TET1, and Parkinson's disease in Chinese Han population.

BMC neurology - 11 Dec 2013

Liao Xin-xin, Zhan Zi-xiong, Luo Ying-ying, Li Kai, Wang Jun-ling, Guo Ji-feng, Yan Xin-xiang, Xia Kun, Tang Bei-sha, Shen Lu

Abstract excerpt

BACKGROUND: Recent studies suggest that epigenetic factors may play an important role in the pathogenesis of Parkinson's disease (PD). In our previous work, we sequenced the exomes of sixteen patients from eight Chinese PD families using whole exome sequencing technology, consequently three patients from different pedigrees were found sharing the variant c.1460C > T (rs150689919) in the coding region of the Tet...

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PMID: 24325350
DOI: 10.1186/1471-2377-13-196
PMCID: PMC4028872

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TET1

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