Article
Epidermal growth-factor-induced transcript isoform variation drives mammary cell migration.
PloS one - 1 Jan 2013
Köstler Wolfgang J, Zeisel Amit, Körner Cindy, Tsai Jonathan M, Jacob-Hirsch Jasmine, Ben-Chetrit Nir, Sharma Kirti, Cohen-Dvashi Hadas, Yitzhaky Assif, Lader Eric, Tschulena Ulrich, Rechavi Gideon, Domany Eytan, Wiemann Stefan, Yarden Yosef
Abstract excerpt
Signal-induced transcript isoform variation (TIV) includes alternative promoter usage as well as alternative splicing and alternative polyadenylation of mRNA. To assess the phenotypic relevance of signal-induced TIV, we employed exon arrays and breast epithelial cells, which migrate in response t...
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