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Article

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.

PloS one - 1 Jan 2013

Deng Xutao, Sabino Ester C, Cunha-Neto Edecio, Ribeiro Antonio L, Ianni Barbara, Mady Charles, Busch Michael P, Seielstad Mark

Abstract excerpt

BACKGROUND: Familial aggregation of Chagas cardiac disease in T. cruzi-infected persons suggests that human genetic variation may be an important determinant of disease progression. OBJECTIVE: To perform a GWAS using a well-characterized cohort to detect single nucleotide polymorphisms (SNPs) and genes associated with cardiac outcomes. METHODS: A retrospective cohort study was developed by the NHLBI REDS-II...

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Identifiers

PMID: 24324551
DOI: 10.1371/journal.pone.0079629
PMCID: PMC3854669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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