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Article

Genomic African and Native American Ancestry and Chagas Disease: The Bambui (Brazil) Epigen Cohort Study of Aging.

PLoS neglected tropical diseases - 1 May 2016

Lima-Costa M Fernanda, Macinko James, Mambrini Juliana Vaz de Mello, Peixoto Sérgio Viana, Pereira Alexandre Costa, Tarazona-Santos Eduardo, Ribeiro Antonio Luiz Pinho

Abstract excerpt

BACKGROUND: The influence of genetic ancestry on Trypanosoma cruzi infection and Chagas disease outcomes is unknown. METHODOLOGY/PRINCIPAL FINDINGS: We used 370,539 Single Nucleotide Polymorphisms (SNPs) to examine the association between individual proportions of African, European and Native American genomic ancestry with T. cruzi infection and related outcomes in 1,341 participants (aged ≥ 60 years) of the...

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Identifiers

PMID: 27182885
DOI: 10.1371/journal.pntd.0004724
PMCID: PMC4868305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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