Article
Proteomic and genomic analyses of antimony resistant Leishmania infantum mutant.
PloS one - 1 Jan 2013
Brotherton Marie-Christine, Bourassa Sylvie, Leprohon Philippe, Légaré Danielle, Poirier Guy G, Droit Arnaud, Ouellette Marc
Abstract excerpt
BACKGROUND: Antimonials remain the primary antileishmanial drugs in most developing countries. However, drug resistance to these compounds is increasing and our understanding of resistance mechanisms is partial. METHODS/PRINCIPAL FINDINGS: In the present study, quantitative proteomics using stabl...
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