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Article

Proteomic and genomic analyses of antimony resistant Leishmania infantum mutant.

PloS one - 1 Jan 2013

Brotherton Marie-Christine, Bourassa Sylvie, Leprohon Philippe, Légaré Danielle, Poirier Guy G, Droit Arnaud, Ouellette Marc

Abstract excerpt

BACKGROUND: Antimonials remain the primary antileishmanial drugs in most developing countries. However, drug resistance to these compounds is increasing and our understanding of resistance mechanisms is partial. METHODS/PRINCIPAL FINDINGS: In the present study, quantitative proteomics using stable isotope labelling of amino acids in cell culture (SILAC) and genome next generation sequencing were used in order to...

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Source

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Identifiers

PMID: 24312377
DOI: 10.1371/journal.pone.0081899
PMCID: PMC3842243

Genes

ABCC3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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