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Article

Integrative genomic, proteomic and phenotypic studies of Leishmania donovani strains revealed genetic features associated with virulence and antimony-resistance.

Parasites & vectors - 12 Oct 2020

Zheng Zhiwan, Chen Jianping, Ma Guangxu, Satoskar Abhay R, Li Jiao

Abstract excerpt

BACKGROUND: Leishmaniasis is a neglected tropical disease affecting millions of people worldwide. Emerging drug resistance of Leishmania species poses threaten to the effective control and elimination programme of this neglected tropical disease. METHODS: In this work, we conducted drug-resistance testing, whole genome resequencing and proteome profiling for a recently reported clinical isolate with supposed drug...

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Identifiers

PMID: 33046138
DOI: 10.1186/s13071-020-04397-4
PMCID: PMC7552375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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