Article
Enhancement of polysialic acid expression improves function of embryonic stem-derived dopamine neuron grafts in Parkinsonian mice.
Stem cells translational medicine - 1 Jan 2014
Battista Daniela, Ganat Yosif, El Maarouf Abderrahman, Studer Lorenz, Rutishauser Urs
Abstract excerpt
There has been considerable progress in obtaining engraftable embryonic stem (ES) cell-derived midbrain dopamine neurons for cell replacement therapy in models of Parkinson's disease; however, limited integration and striatal reinnervation of ES-derived grafts remain a major challenge for future...
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