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Article

Gas6 Promotes Inflammatory (CCR2hiCX3CR1lo) Monocyte Recruitment in Venous Thrombosis.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2017

Laurance Sandrine, Bertin François-René, Ebrahimian Talin, Kassim Yusra, Rys Ryan N, Lehoux Stéphanie, Lemarié Catherine A, Blostein Mark D

Abstract excerpt

OBJECTIVE: Coagulation and inflammation are inter-related. Gas6 (growth arrest-specific 6) promotes venous thrombosis and participates to inflammation through endothelial-innate immune cell interactions. Innate immune cells can provide the initiating stimulus for venous thrombus development. We hypothesize that Gas6 promotes monocyte recruitment during venous thrombosis. APPROACH AND RESULTS: Deep venous...

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Source

Identifiers

PMID: 28450294
DOI: 10.1161/ATVBAHA.116.308925

Genes

CCL2
CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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