Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Digital Genomic Quantification of Tumor-Infiltrating Lymphocytes

4 Dec 2013

Abstract excerpt

Infiltrating T lymphocytes are frequently found in malignant tumors and are suggestive of a host cancer immune response. Multiple independent studies have documented that the presence and quantity of tumor-infiltrating lymphocytes (TILs) are strongly correlated with increased survival. However, because of methodological factors, the exact effect of TILs on prognosis has remained enigmatic, and inclusion of TILs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Immune Cell Function and Interaction
Share to Immunotherapy and Immune Responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24307693
DOI: 10.1126/scitranslmed.3007247

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Digital Genomic Quantification of Tumor-Infiltrating LymphocytesPMID 24307693Read ↗

High‐throughput sequencing of T‐cell receptors reveals a homogeneous repertoire of tumour‐infiltrating lymphocytes in ovarian cancerSemantic proximity Read ↗

New insights into tumor immunity revealed by the unique genetic and genomic aspects of ovarian cancer.Semantic proximity Read ↗

The mutational load and a T-cell inflamed tumor phenotype identify ovarian cancer patients rendering tumor-reactive T cells from PD-1+ tumor-infiltrating lymphocytesSemantic proximity Read ↗

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors.Semantic proximity Read ↗

Characterization of T cell repertoire of blood, tumor, and ascites in ovarian cancer patients using next generation sequencingSemantic proximity Read ↗

The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes.Semantic proximity Read ↗

3D amplified single-cell RNA and protein imaging identifies oncogenic transcript subtypes in B cell acute lymphoblastic leukemiaSemantic proximity Read ↗

Minimal residual disease detection by mutation-specific droplet digital PCR for leukemia/lymphoma.Semantic proximity Read ↗

Circulating Tumor DNA–Based MRD Assessment in Patients with CLL Treated with Obinutuzumab, Acalabrutinib, and VenetoclaxSemantic proximity Read ↗

Digital PCR for Minimal Residual Disease Quantitation Using Immunoglobulin/T-Cell Receptor Gene Rearrangements in Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Immune DNA signature of T-cell infiltration in breast tumor exomesSemantic proximity Read ↗

Immune DNA signature of T-cell infiltration in breast tumor exomesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.