Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Repression of choroidal neovascularization through actin cytoskeleton pathways by microRNA-24.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Feb 2014

Zhou Qinbo, Anderson Chastain, Zhang Hongmei, Li Xinyu, Inglis Fiona, Jayagopal Ashwath, Wang Shusheng

Abstract excerpt

Actin cytoskeleton is critical for cell motility and division, both of which are important for angiogenesis. MicroRNAs (miRNA/miR) are emerging as pivotal modulators of vascular development and disease. How miRNAs regulate actin cytoskeleton dynamics in endothelial cells (EC) and neovascularization is still unclear. Here, we report that miR-24 regulates actin dynamics in ECs through targeting multiple members...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Actin Cytoskeleton

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Choroidal Neovascularization

Share to Endothelial Cells

Share to Gene Silencing

Share to Lim Kinases

Share to p21-Activated Kinases

Share to RNA Interference

Source

Open in PubMed Open full text

Identifiers

PMID: 24297048
DOI: 10.1038/mt.2013.243
PMCID: PMC3916039

Genes

LIMK2
PAK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Repression of choroidal neovascularization through actin cytoskeleton pathways by microRNA-24.PMID 24297048Read ↗

Regulation of angiogenin expression and epithelial-mesenchymal transition by HIF-1α signaling in hypoxic retinal pigment epithelial cellsSemantic proximity Read ↗

Myofibroblast lineage mapping and inhibiting subretinal fibrosis by targeting SMAD3 and MRTF pathways via microRNA-24 functional studySemantic proximity Read ↗

MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1ASemantic proximity Read ↗

A new role for cofilin in retinal neovascularizationSemantic proximity Read ↗

NCK Associated Protein 1 Modulated by miRNA-214 Determines Vascular Smooth Muscle Cell Migration, Proliferation, and Neointima Hyperplasia.Semantic proximity Read ↗

p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2-stimulated angiogenesis.Semantic proximity Read ↗

SNAI1, an endothelial–mesenchymal transition transcription factor, promotes the early phase of ocular neovascularizationSemantic proximity Read ↗

MicroRNA-34a suppresses KLF2 to promote pathological angiogenesis through the CXCR4/CXCL12 pathway in age-related macular degenerationSemantic proximity Read ↗

Coordinate control of proliferation and migration by the p27Kip1/cyclin-dependent kinase/retinoblastoma pathway in vascular smooth muscle cells and fibroblasts.Semantic proximity Read ↗

Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal NeovascularizationSemantic proximity Read ↗

Angiopoietin-1 is regulated by miR-204 and contributes to corneal neovascularization in KLEIP-deficient mice.Semantic proximity Read ↗

Genome Editing VEGFA Prevents Corneal Neovascularization In VivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.