Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apelin is required for non-neovascular remodeling in the retina.

The American journal of pathology - 1 Jan 2012

McKenzie Jenny A G, Fruttiger Marcus, Abraham Sabu, Lange Clemens A K, Stone Jay, Gandhi Pranita, Wang Xiaomeng, Bainbridge James, Moss Stephen E, Greenwood John

Abstract excerpt

Retinal pathologies are frequently accompanied by retinal vascular responses, including the formation of new vessels by angiogenesis (neovascularization). Pathological vascular changes may also include less well characterized traits of vascular remodeling that are non-neovascular, such as vessel pruning and the emergence of dilated and tortuous vessel phenotypes (telangiectasis). The molecular mechanisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines
Share to Choroidal Neovascularization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Silencing

Share to Intercellular Signaling Peptides and Proteins

Share to Microvessels

Share to Retina

Share to Retinal Degeneration

Share to Retinal Vessels

Source

Open in PubMed Open full text

Identifiers

PMID: 22067912
DOI: 10.1016/j.ajpath.2011.09.035
PMCID: PMC3244602

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apelin is required for non-neovascular remodeling in the retina.PMID 22067912Read ↗

Retardation of retinal vascular development in apelin-deficient mice.Semantic proximity Read ↗

Argon Laser Photocoagulation–Induced Modification of Gene Expression in the RetinaSemantic proximity Read ↗

Transcriptional Comparison of Human and Murine Retinal NeovascularizationSemantic proximity Read ↗

Development and pathology of the hyaloid, choroidal and retinal vasculature.Semantic proximity Read ↗

AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch SignalingSemantic proximity Read ↗

Atypical p38 Kinase Signaling in Retinal Vascular Damage and RecoverySemantic proximity Read ↗

Clinical Pathological Features and Current Animal Models of Type 3 Macular NeovascularizationSemantic proximity Read ↗

Mouse model of subretinal neovascularization with choroidal anastomosis.Semantic proximity Read ↗

Gene Expression Within a Human Choroidal Neovascular Membrane Using Spatial TranscriptomicsSemantic proximity Read ↗

Molecular Mediators and Regulators of Retinal AngiogenesisSemantic proximity Read ↗

GENE EXPRESSION WITHIN A HUMAN CHOROIDAL NEOVASCULAR MEMBRANE USING SPATIAL TRANSCRIPTOMICSSemantic proximity Read ↗

The vascular gene <i>Apold1</i> is dispensable for normal development but controls angiogenesis under pathological conditionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.