Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A

10 Mar 2020

Abstract excerpt

Pathologic ocular neovascularization commonly results in visual impairment or even blindness in numerous fundus diseases, including proliferative diabetic retinopathy (PDR), retinopathy of prematurity (ROP), and age-related macular degeneration (AMD). MicroRNAs regulate angiogenesis through modulating target genes and disease progression, making them a new class of targets for drug discovery. In this study, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation
Share to Pregnancy and preeclampsia studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32210827
DOI: 10.3389/fphar.2020.00276

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1APMID 32210827Read ↗

Retinal expression of small non-coding RNAs in a murine model of proliferative retinopathySemantic proximity Read ↗

MicroRNA-410 Reduces the Expression of Vascular Endothelial Growth Factor and Inhibits Oxygen-Induced Retinal NeovascularizationSemantic proximity Read ↗

Molecular Mediators and Regulators of Retinal AngiogenesisSemantic proximity Read ↗

MicroRNA expression profile in retina and choroid in oxygen-induced retinopathy modelSemantic proximity Read ↗

The Long-Noncoding RNA TUG1 Regulates Oxygen-Induced Retinal Neovascularization in Mice via MiR-299Semantic proximity Read ↗

MiR-375 mitigates retinal angiogenesis by depressing the JAK2/STAT3 pathwaySemantic proximity Read ↗

MicroRNAs in Vascular Eye Diseases.Semantic proximity Read ↗

Upregulated VEGF and Robo4 correlate with the reduction of miR-15a in the development of diabetic retinopathySemantic proximity Read ↗

Decoding Noncoding RNAs: Role of MicroRNAs and Long Noncoding RNAs in Ocular NeovascularizationSemantic proximity Read ↗

Exploration of Oxygen-Induced Retinopathy Model to Discover New Therapeutic Drug Targets in RetinopathiesSemantic proximity Read ↗

Hypoxia-Inducible Factor-1 (HIF-1): A Potential Target for Intervention in Ocular Neovascular DiseasesSemantic proximity Read ↗

Short Hairpin RNA-Mediated Knockdown of VEGFA in Müller Cells Reduces Intravitreal Neovascularization in a Rat Model of Retinopathy of PrematuritySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.