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Article

The effects of shRNA-mediated gene silencing of transcription factor SNAI1 on the biological phenotypes of breast cancer cell line MCF-7.

Molecular and cellular biochemistry - 1 Mar 2014

Lu Yan, Yu Lina, Yang Minlan, Jin Xiangshu, Liu Zhijing, Zhang Xiaowei, Wang Liping, Lin Dongjing, Liu Yuanyuan, Wang Min, Quan Chengshi

Abstract excerpt

To research the effects of silencing transcription factor SNAI1 on the in vitro biological phenotypes of breast cancer cell line MCF-7, based on the gene sequence of SNAI1, we linked shRNA with the green fluorescent protein-expressing eukaryotic expression vector pGCsilencer™ U6/Neo/GFP, and transfected it into MCF-7 cells. The SNAI1 gene-silencing effect was authenticated by RT-PCR and immunofluorescence. We...

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Identifiers

PMID: 24293287
DOI: 10.1007/s11010-013-1903-4

Genes

SNAI1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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