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Article

FBW7 increases chemosensitivity in hepatocellular carcinoma cells through suppression of epithelial-mesenchymal transition.

Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Apr 2014

Yu Jun, Zhang Wu, Gao Feng, Liu Yuan-Xing, Chen Zhi-Yun, Cheng Long-Yu, Xie Shang-Fen, Zheng Shu-Sen

Abstract excerpt

BACKGROUND: FBW7 is a tumor suppressor which regulates a network of proteins with central roles in cell division, cell growth and differentiation. This study aimed to evaluate the role of FBW7 in chemosensitivity and epithelial-mesenchymal transition (EMT) in different hepatocellular carcinoma (HCC) cell lines and to investigate the relevant underlying mechanisms. METHODS: Different human HCC cell lines (Hep3B,...

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Identifiers

PMID: 24686546
DOI: 10.1016/s1499-3872(14)60029-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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