Article
Investigation of ICAM-1 and β3 integrin gene variations in patients with brain tumors.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Yilmaz Umit, Zeybek Umit, Kahraman Ozlem Timirci, Kafadar Ali Metin, Toptas Bahar, Yamak Nesibe, Celik Faruk, Yaylim Ilhan
Abstract excerpt
BACKGROUND: Primary brain tumors constitute a small percent of all malignant cancers, but their etiology remains poorly understood. β3 integrin (ITGB3) has been recognized to play influential roles in angiogenesis, tumor growth and metastasis. Intercellular adhesion molecule-1 (ICAM-1) is a surface glycoprotein important for tumor invasion and angiogenesis. The aim of this study was to investigate whether...
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