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Article

Analysis of CASP8 D302H Gene Variants in Patients with Primary Brain Tumors.

In vivo (Athens, Greece) - 1 Jan 2000

Cacina Canan, Pence Sadrettin, Turan Saime, Genc Feyza, Ozdemir Hulya, Kafadar Ali, Kaynar Mehmet Yasar, Yaylim Ilhan

Abstract excerpt

BACKGROUND: Alteration in cell-cycle control and apoptosis pathways play important roles in tumorigenesis. Caspase-8 (CASP8) is a member of the cysteine protease family, that is implicated in apoptosis regulation. The present study was designed to investigate the possible role of CASP8 D302H gene polymorphism in the tumor development. MATERIALS AND METHODS: A total of 91 patients with brain tumors (including 39...

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Identifiers

PMID: 26359420

Genes

CASP8

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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