Article
Association between interleukin 8-251 T/A and +781 C/T polymorphisms and glioma risk.
Diagnostic pathology - 7 Aug 2015
Liu Hao, Mao Ping, Xie Changhou, Xie Wanfu, Wang Maode, Jiang Haitao
Abstract excerpt
BACKGROUND: Gliomas are aggressive tumors of the central nervous system that rely on production of growth factors for tumor progression. Interleukin 8 (IL-8) is up-regulated in gliomas to promote angiogenesis and proliferation. The aim of this study was to evaluate the association of the IL-8 -251 T/A and +781 C/T polymorphisms and glioma risk. METHODS: We enrolled 300 glioma patients and 300 age- and...
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