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Association of cagA-Positive Helicobacter pylori with MGMT Promoter Hypermethylation Across the Gastric Disease Spectrum and Gastric Cancer

2026-02-03

Abstract excerpt

Background Epigenetic alteration through promoter DNA methylation is associated with gastric carcinogenesis. This study assessed the association between Helicobacter pylori infection, specifically cagA -positive strains, and MGMT promoter hypermethylation within the gastroduodenal disease spectrum in an Iraqi cohort. Methods The study conducted a case control study of 120 participants (40 endoscopy confirmed co...

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Literature Corpus work
18be3303-27d5-5bc1-ad01-8d24c1b2ebbc
DOI
10.12688/f1000research.175170.1
Open publication

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Association of cagA-Positive Helicobacter pylori with MGMT Promoter Hypermethylation Across the Gastric Disease Spectrum and Gastric CancerDOI 10.12688/f1000research.175170.1
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