Article
Photocrosslinkable laminin-functionalized polyethylene glycol hydrogel for intervertebral disc regeneration.
Acta biomaterialia - 1 Mar 2014
Francisco Aubrey T, Hwang Priscilla Y, Jeong Claire G, Jing Liufang, Chen Jun, Setton Lori A
Abstract excerpt
Intervertebral disc (IVD) disorders and age-related degeneration are believed to contribute to lower back pain. There is significant interest in cell-based strategies for regenerating the nucleus pulposus (NP) region of the disc; however, few scaffolds have been evaluated for their ability to promote or maintain an immature NP cell phenotype. Previous studies have shown that NP cell-laminin interactions promote...
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