Article
Understanding the native nucleus pulposus cell phenotype has important implications for intervertebral disc regeneration strategies.
Regenerative medicine - 1 Jan 2013
Ludwinski Francesca E, Gnanalingham Kanna, Richardson Stephen M, Hoyland Judith A
Abstract excerpt
Low back pain is a leading cause of morbidity in developed societies and is strongly linked to degeneration of the intervertebral disc. The central nucleus pulposus (NP) region is most severely affected during disc degeneration and, consequently, is a focus for novel cell-based regenerative strategies. However, in order to develop such techniques, it is essential to first understand the biology and phenotype of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.