Article
Association of the lipoprotein receptor-related protein 2 gene with gout and non-additive interaction with alcohol consumption.
Arthritis research & therapy - 4 Nov 2013
Rasheed Humaira, Phipps-Green Amanda, Topless Ruth, Hollis-Moffatt Jade E, Hindmarsh Jennie Harré, Franklin Christopher, Dalbeth Nicola, Jones Peter B, White Douglas H N, Stamp Lisa K, Merriman Tony R
Abstract excerpt
INTRODUCTION: The T allele of a single nucleotide polymorphism (SNP: rs2544390) in lipoprotein receptor-related protein 2 (LRP2) is associated with higher serum urate and risk of gout in Japanese individuals. SNP rs2544390 also interacts with alcohol consumption in determining hyperuricemia in th...
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