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Article

Association of the lipoprotein receptor-related protein 2 gene with gout and non-additive interaction with alcohol consumption.

Arthritis research & therapy - 4 Nov 2013

Rasheed Humaira, Phipps-Green Amanda, Topless Ruth, Hollis-Moffatt Jade E, Hindmarsh Jennie Harré, Franklin Christopher, Dalbeth Nicola, Jones Peter B, White Douglas H N, Stamp Lisa K, Merriman Tony R

Abstract excerpt

INTRODUCTION: The T allele of a single nucleotide polymorphism (SNP: rs2544390) in lipoprotein receptor-related protein 2 (LRP2) is associated with higher serum urate and risk of gout in Japanese individuals. SNP rs2544390 also interacts with alcohol consumption in determining hyperuricemia in this population. We investigated the association of rs2544390 with gout, and interaction with all types of alcohol...

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Share to Adaptor Proteins, Signal Transducing
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Source

Open in PubMed Open full text

Identifiers

PMID: 24286387
DOI: 10.1186/ar4366
PMCID: PMC3979038

Genes

LRP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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