The rs2231142 variant of the ABCG2 gene is associated with uric acid levels and gout among Japanese people.

doi:10.1093/rheumatology/keq096

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The rs2231142 variant of the ABCG2 gene is associated with uric acid levels and gout among Japanese people.

Rheumatology (Oxford, England) - 1 Aug 2010

Yamagishi Kazumasa, Tanigawa Takeshi, Kitamura Akihiko, Köttgen Anna, Folsom Aaron R, Iso Hiroyasu

Abstract excerpt

OBJECTIVES: Recent genome-wide association and functional studies have shown that the ABCG2 gene encodes for a urate transporter, and a common causal ABCG2 variant, rs2231142, leads to elevated uric acid levels and prevalent gout among Whites and Blacks. We examined whether this finding is observed in a Japanese population, since Asians have a high reported prevalence of the T-risk allele. METHODS: A total of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily G, Member 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP-Binding Cassette Transporters

Share to Gout

Share to Hyperuricemia

Share to Multivariate Analysis

Share to Neoplasm Proteins

Share to Organic Anion Transporters

Share to Uric Acid

Source

Open in PubMed

Identifiers

PMID: 20421215
DOI: 10.1093/rheumatology/keq096

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The rs2231142 variant of the ABCG2 gene is associated with uric acid levels and gout among Japanese people.PMID 20421215Read ↗

Association of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study.Semantic proximity Read ↗

ABCG2 rs2231142 variant in hyperuricemia is modified by SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors in an elderly community-dwelling population.Semantic proximity Read ↗

Association of ABCG2 rs2231142-A allele and serum uric acid levels in male and obese individuals in a Han Taiwanese population.Semantic proximity Read ↗

The association between the polymorphism rs2231142 in the ABCG2 gene and gout risk: a meta-analysis.Semantic proximity Read ↗

Association of ABCG2 rs2231142 Allele and BMI With Hyperuricemia in an East Asian PopulationSemantic proximity Read ↗

Polymorphisms of uric transporter proteins in the pathogenesis of gout in a Chinese Han population.Semantic proximity Read ↗

The ABCG2 rs2231142 polymorphism and the risk of nephrolithiasis: A case-control study from the Taiwan biobank.Semantic proximity Read ↗

Analysis of ABCG2 gene rs2231142 single nucleotide polymorphism and risk factors in hyperuricemiaSemantic proximity Read ↗

The prevalence of the gout-associated polymorphism rs2231142 G>T in ABCG2 in a pregnant female Filipino cohort.Semantic proximity Read ↗

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.Semantic proximity Read ↗

The association between genetic polymorphisms in ABCG2 and SLC2A9 and urate: an updated systematic review and meta-analysis.Semantic proximity Read ↗

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.