Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of genetic variation at ADH1B and MLXIPL with alcohol consumption for elevated serum urate level and gout among people of European ethnicity.

Arthritis research & therapy - 8 Feb 2024

Chuah Min H, Leask Megan P, Topless Ruth K, Gamble Gregory D, Sumpter Nicholas A, Stamp Lisa K, Merriman Tony R, Dalbeth Nicola

Abstract excerpt

BACKGROUND: Alcohol consumption is a risk factor for hyperuricaemia and gout. Multiple single-nucleotide polymorphisms (SNPs) have been identified as associated with both alcohol consumption and serum urate or gout in separate genome-wide association studies (GWAS). This study aimed to identify and characterise interactions between these shared signals of genetic association and alcohol consumption for serum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Dehydrogenase
Share to Alcohol Drinking

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ethnicity

Share to Genome-Wide Association Study

Share to Hyperuricemia

Share to Transcription Factors

Share to Uric Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 38331848
DOI: 10.1186/s13075-024-03279-9
PMCID: PMC10851571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of genetic variation at ADH1B and MLXIPL with alcohol consumption for elevated serum urate level and gout among people of European ethnicity.PMID 38331848Read ↗

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).Semantic proximity Read ↗

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117)Semantic proximity Read ↗

Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout.Semantic proximity Read ↗

Phenome-wide study on alcohol consumption provides genetic evidence for a causal association with multiple diseases and biomarkers.Semantic proximity Read ↗

Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.Semantic proximity Read ↗

Molecular Alterations Caused by Alcohol Consumption: A Mendelian Randomisation StudySemantic proximity Read ↗

Are polymorphisms affecting serum urate, renal urate handling and alcohol intake associated with co-morbidities in gout cases? A case-control study using data from the UK Biobank.Semantic proximity Read ↗

Molecular Alterations Caused by Alcohol Consumption in the UK Biobank: A Mendelian Randomisation Study.Semantic proximity Read ↗

Alcohol consumption and risks of more than 200 diseases in Chinese men.Semantic proximity Read ↗

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.Semantic proximity Read ↗

Alcohol intake.Semantic proximity Read ↗

Interaction of alcohol consumption and genetic variants in alcohol metabolism on all-cause and disease-specific mortality: a cohort studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.