Article
The relationship between endothelial nitric oxide synthase 4a/4b gene polymorphism and premature coronary artery disease.
Acta cardiologica - 1 Oct 2013
Ekmekçi Ahmet, Ozcan Kazim Serhan, Güngör Bariş, Abaci Neslihan, Osmonov Damirbek, Zencirci Aycan, Toprak Ercan, Dönmez Cevdet, Ustek Duran, Güleç Cağri, Eren Mehmet
Abstract excerpt
BACKGROUND: Nitric oxide (NO) plays a major role in the regulation of endothelial functions and reduced NO synthesis has been implicated in the development of coronary atherosclerosis. Endothelial nitric oxide synthase (eNOS) intron 4a/b polymorphism has been shown to be related to plasma nitric oxide concentrations and coronary artery disease in various population studies. The aim of this study is to assess the...
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