Article
Lack of association between endothelial nitric oxide synthase gene polymorphisms and risk of premature coronary artery disease in the Greek population.
Acta cardiologica - 1 Oct 2008
Vasilakou Magda, Votteas Vasilios, Kasparian Charoutiun, Pantazopoulos Nikos, Dedoussis George, Deltas Constantinos, Nastos Panagiotis, Nikolakis Dimitris, Lamnissou Klea
Abstract excerpt
OBJECTIVE: Genetic polymorphisms in the gene for endothelial nitric oxide synthase have been considered as potential risk factors for the development of coronary artery disease in some populations. METHODS: We studied two polymorphisms of the NOS3 gene, the VNTR in intron 4 (4VNTR) and the Glu298Asp polymorphism in exon 7, in relation to the existence of premature coronary artery disease and the occurrence of...
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