Article
Association between the Glu298Asp and 4b/4a polymorphisms of endothelial nitric oxide synthase and coronary slow flow in the North Indian population.
Coronary artery disease - 1 May 2014
Gupta Mohit D, Akkarappatty Cherian, Girish Meenahalli P, Kumar Rahul, Rain Manjari, Tyagi Sanjay, Qadar Pasha Mohammed A
Abstract excerpt
RATIONALE: Genetic variants in endothelial nitric oxide synthase gene (NOS3) leading to endothelial dysfunction may be predispose to the coronary slow-flow phenomenon (CSFP). METHODS AND RESULTS: In this study, we examined the relationship between Glu298Asp (894G/T) and 4b/4a polymorphisms of NOS3 and CSFP. A total of 27 patients with CSFP but otherwise normal coronary arteries (mean age 50.4±8.2 years) and 200...
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