Article
Association of a 27-bp repeat polymorphism in intron 4 of endothelial constitutive nitric oxide synthase gene with myocardial infarction in Tunisian patients.
Clinical chemistry and laboratory medicine - 1 Jan 2007
Jemaa Riadh, Kallel Amani, Ben Ali Samir, Omar Souheil, Chabrak Sonia, Elasmi Monia, Haj Taieb Sameh, Sanhaji Haïfa, Feki Moncef, Mechmeche Rachid, Kaabachi Naziha
Abstract excerpt
BACKGROUND: Nitric oxide (NO) produced by endothelial nitric oxide synthase (eNOS) mediates endothelium-dependent vasodilatation and antithrombotic action. Controversial results regarding the association of eNOS gene (NOS3) polymorphisms with myocardial infarction (MI) have been reported. In the present study, we examined a possible association between a 27-base pair (bp) repeat polymorphism in intron 4 of the...
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