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Article

A transcriptomic approach to elucidate the physiological significance of human cytochrome P450 2S1 in bronchial epithelial cells.

BMC genomics - 26 Nov 2013

Madanayake Thushara W, Lindquist Ingrid E, Devitt Nicholas P, Mudge Joann, Rowland Aaron M

Abstract excerpt

BACKGROUND: Cytochrome P450 2S1 (CYP2S1) is an orphan P450 with an unknown biological function. Data from our laboratory and others suggest that CYP2S1 may have an important physiological role in modulating the synthesis and metabolism of bioactive lipids including prostaglandins and retinoids. CYP2S1 expression is elevated in multiple epithelial-derived cancers as well as in the chronic hyperproliferative...

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Identifiers

PMID: 24279958
DOI: 10.1186/1471-2164-14-833
PMCID: PMC3884200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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