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CYP2S1 might regulate proliferation and immune response of keratinocyte in psoriasis

12 Sept 2020

Abstract excerpt

Psoriasis is an autoimmune skin disorder influenced by genetic, epigenetic and environmental factors. We previously found CYP2S1 intragenic DNA methylation cg19430423 site strongly hypomethylated in psoriatic skin tissues. In this study, we performed methylation loci fine-mapping to search the top signals in the entire CYP2S1 gene region, and further carried out gene expression assay, cell proliferation,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32924783
DOI: 10.1080/15592294.2020.1814486

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