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Article

A miRNA binding site single-nucleotide polymorphism in the 3'-UTR region of the IL23R gene is associated with breast cancer.

PloS one - 1 Jan 2012

Wang Lihong, Liu Wei, Jiang Wei, Lin Jing, Jiang Yongdong, Li Bo, Pang Da

Abstract excerpt

BACKGROUND: Research into the etiology of breast cancer has recently focused on the role of the immunity and inflammation. Interleukin-23 and its receptor (IL23R) guide T cells towards the Th17 phenotype. IL23R single nucleotide polymorphisms (SNPs) have been shown to be associated with digestive system cancers. To evaluate the influences of IL23R gene polymorphisms on the risk of sporadic breast cancer, a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23239971
DOI: 10.1371/journal.pone.0049823
PMCID: PMC3519811

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