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Article

A FUT2 gene common polymorphism determines resistance to rotavirus A of the P[8] genotype.

The Journal of infectious diseases - 15 Apr 2014

Imbert-Marcille Berthe-Marie, Barbé Laure, Dupé Mathilde, Le Moullac-Vaidye Béatrice, Besse Bernard, Peltier Cécile, Ruvoën-Clouet Nathalie, Le Pendu Jacques

Abstract excerpt

Attachment to carbohydrates of the histo-blood group type of several human Rotavirus strains (RVA) has recently been described. Synthesis of these ligands requires a functional FUT2 enzyme, suggesting that FUT2 null homozygote (ie, nonsecretor) individuals may not be recognized by most human RVA strains. Whereas such individuals represent 20% of the control population, this retrospective study determined that...

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Identifiers

PMID: 24277741
DOI: 10.1093/infdis/jit655

Genes

FUT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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