Article
Host-Range Shift Between Emerging P[8]-4 Rotavirus and Common P[8] and P[4] Strains.
The Journal of infectious diseases - 4 Aug 2020
Khachou Amira, Le Moullac-Vaidye Béatrice, Peltier Cécile, Breiman Adrien, Imbert-Marcille Berthe-Marie, Ruvoen-Clouet Nathalie, Aouni Mahjoub, Mastouri Maha, Chouchane Slaheddine, Le Pendu Jacques
Abstract excerpt
In Tunisia, we observed that rotavirus P[8]-3 and P[4] strains in young children with gastroenteritis associate with secretor histo-blood group phenotype. In contrast, the emerging P[8]-4 strain, representing 10% of cases, was exclusively found in nonsecretor patients. Unlike VP8* from P[8]-3 and P[4] strains, the P[8]-4 VP8* protein attached to glycans from saliva samples regardless of the donor's secretor...
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