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Article

Human susceptibility and resistance to Norwalk virus infection.

Nature medicine - 1 May 2003

Lindesmith Lisa, Moe Christine, Marionneau Severine, Ruvoen Nathalie, Jiang Xi, Lindblad Lauren, Stewart Paul, LePendu Jacques, Baric Ralph

Abstract excerpt

Infectious diseases have influenced population genetics and the evolution of the structure of the human genome in part by selecting for host susceptibility alleles that modify pathogenesis. Norovirus infection is associated with approximately 90% of epidemic non-bacterial acute gastroenteritis worldwide. Here, we show that resistance to Norwalk virus infection is multifactorial. Using a human challenge model, we...

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Source

Identifiers

PMID: 12692541
DOI: 10.1038/nm860

Genes

FUT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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