Article
Ancestral FUT2 genetic adaptation confers resistance to modern norovirus and rotavirus infections.
Current opinion in virology - 1 Apr 2026
Nordgren Johan, Ågren Richard, Hagbom Marie, Zeberg Hugo, Svensson Lennart
Abstract excerpt
Human genetic diversity plays a key role in modulating susceptibility to infectious diseases, reflecting a long history of host-pathogen co-evolution. While clinical outcomes were once attributed primarily to pathogen virulence, evidence today underscores the impact of host genes in infection susceptibility. Noroviruses and rotaviruses, leading causes of acute gastroenteritis, illustrate this dynamic interplay....
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