Article
Members of the conserved DedA family are likely membrane transporters and are required for drug resistance in Escherichia coli.
Antimicrobial agents and chemotherapy - 1 Jan 2014
Kumar Sujeet, Doerrler William T
Abstract excerpt
Bacterial resistance to antibiotics and biocides is an increasing public health problem. Genes encoding integral membrane proteins belonging to the DedA family are present in most bacterial genomes, including Escherichia coli. An E. coli strain lacking partially redundant DedA family genes yqjA and yghB (strain BC202) displays temperature sensitivity and cell division defects. These phenotypes can be corrected by...
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