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Article

Distribution and Physiology of ABC-Type Transporters Contributing to Multidrug Resistance in Bacteria

1 Sept 2007

Abstract excerpt

Membrane proteins responsible for the active efflux of structurally and functionally unrelated drugs were first characterized in higher eukaryotes. To date, a vast number of transporters contributing to multidrug resistance (MDR transporters) have been reported for a large variety of organisms. Predictions about the functions of genes in the growing number of sequenced genomes indicate that MDR transporters are...

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PMID: 17804667
DOI: 10.1128/mmbr.00001-07

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