Article

The RND efflux pump EefABC is highly conserved within lineages of <i>E. coli</i> commonly associated with infection

2024-08-01

Abstract excerpt

Tripartite resistance-nodulation-division (RND) efflux pumps confer multidrug resistance (MDR) in Gram-negative bacteria and are critical for many physiological functions including virulence and biofilm formation. The common laboratory strain of E. coli, K-12 MG1655 has six recognised RND transporters participating in tripartite pump formation (AcrB, AcrD, AcrF, CusA, MdtBC, and MdtF). However, by studying >20,00...

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Literature Corpus work: 283e57ff-7996-5562-a609-ba55f2b2176a
DOI: 10.1101/2024.08.01.606150

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