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A DedA Family Membrane Protein Is Required for Burkholderia thailandensis Colistin Resistance

5 Nov 2019

Abstract excerpt

Colistin is a “last resort” antibiotic for treatment of infections caused by some multidrug resistant Gram-negative bacterial pathogens. Resistance to colistin varies between bacterial species. Some Gram-negative bacteria such as Burkholderia spp. are intrinsically resistant to very high levels of colistin with minimal inhibitory concentrations often above 0.5 mg/ml. We have previously shown DedA family proteins...

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PMID: 31827463
DOI: 10.3389/fmicb.2019.02532

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