Article
Identification of essential arginine residues of Escherichia coli DedA/Tvp38 family membrane proteins YqjA and YghB.
FEMS microbiology letters - 1 Jul 2016
Kumar Sujeet, Bradley Cersten L, Mukashyaka Patience, Doerrler William T
Abstract excerpt
Escherichia coli DedA/Tvp38 family proteins YghB and YqjA are putative membrane transporters with 62% amino acid identity and overlapping functions. An E. coli strain (BC202) with nonpolar ΔyghB and ΔyqjA mutations displays cell-division defects and temperature sensitivity and is sensitive to antibiotics and alkaline pH. In this study, we performed site-directed mutagenesis on conserved, charged amino acids of...
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