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Article

A catalytically essential motif in external loop 5 of the bacterial oligosaccharyltransferase PglB.

The Journal of biological chemistry - 10 Jan 2014

Lizak Christian, Gerber Sabina, Zinne Daria, Michaud Gaëlle, Schubert Mario, Chen Fan, Bucher Monika, Darbre Tamis, Zenobi Renato, Reymond Jean-Louis, Locher Kaspar P

Abstract excerpt

Asparagine-linked glycosylation is a post-translational protein modification that is conserved in all domains of life. The initial transfer of a lipid-linked oligosaccharide (LLO) onto acceptor asparagines is catalyzed by the integral membrane protein oligosaccharyltransferase (OST). The previously reported structure of a single-subunit OST enzyme, the Campylobacter lari protein PglB, revealed a partially...

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Identifiers

PMID: 24275651
DOI: 10.1074/jbc.M113.524751
PMCID: PMC3887201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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